The state has become a hub for chip makers including Intel and TSMC, as the government prepares to release a gusher of funds for the strategic industry.
A 2011 mass shooting left Gabrielle Giffords, then a Democratic congresswoman, partly paralyzed and unable to speak fluently. She has since built a powerful advocacy group.
Mr. Kelly, who ran as a bipartisan legislator devoted to the needs of Arizona, defeated Blake Masters, a Republican newcomer whose ideological fervor failed to win over enough independent voters.