The rap producer known as Pone, who has A.L.S., speaks through a computer that makes him sound robotic. He asked a comic impersonator to try to recapture his distinctive sound.
The drug is safe, and one trial found it may extend survival and slow paralysis in functions like muscle control and speaking. A larger trial will be completed in 2024.
The Calgary Flames executive has lived with A.L.S. since 2019. The team he helped build is in the N.H.L. playoffs, and he is still here to see whatever happens.
With a 6-4 vote, the group of independent advisers to the agency narrowly concluded that results from another clinical trial are needed to assess whether the therapy, called AMX0035, can help patients.