JAN HOFFMAN

Tianeptine, found at convenience stores, at smoke shops and online, can mimic an opioid. It is among a growing class of substances that are difficult...

The court will decide whether Purdue’s owners can gain permanent immunity from future opioid lawsuits in exchange for payments up to $6 billion.

As states and counties spend the first wave of billions of dollars from the pharmaceutical industry, public health groups are challenging how some funds are...

Critics say a fierce law-and-order approach could undermine public health goals and advances in addiction treatment.

In return for the shield, the billionaire owners of Purdue Pharma are committed to paying up to $6 billion to help compensate communities and individuals...

The decision gives the Purdue Pharma owners long-sought protection, but it will release billions of dollars from their fortune to states and communities to help...

Black patients with opioid use disorder were far less likely to fill prescriptions for the most effective addiction treatments than white patients. But strikingly few...

Drug dealers are mixing xylazine, an animal tranquilizer relied on by veterinarians, into fentanyl, with deadly results. But controlling it is tricky.

The F.D.A.’s decision to allow the overdose-reversing nasal spray to be sold over the counter means it will become much more widely available. Here is...

The nasal spray reverses opioid overdoses and public health officials hope that making it more widely available could save lives and reduce the nation’s high...