GINA KOLATA

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An Ultrasound Experiment Tackles a Giant Problem in Brain Medicine

The effects of drugs that treat Alzheimer’s, cancer and other illnesses are often limited by the blood-brain barrier. A small study suggests a way forward.

Ozempic and Wegovy Users Had Less Risk of Suicidal Thoughts in Large Study

The research, supported by the National Institutes of Health, may reassure some patients after a European drug safety agency raised concerns last year.

New Drugs Can Fix Teenage Obesity, but Young People Don’t Get Them

Pediatricians are hesitating to prescribe medicines like Wegovy, citing their newness and uncertainties around them.

F.D.A. Approves 2 Sickle Cell Treatments, One Using CRISPR Gene Editing

People with the genetic disease have new opportunities to eliminate their symptoms, but the treatments come with obstacles that limit their reach.

CAR-T, Lifesaving Cancer Treatment, May Sometimes Cause Cancer, FDA Says

The agency is looking into reports that some patients developed new blood cancers after receiving CAR-T treatments.

Sickle-Cell Treatment Created With Gene Editing Wins U.K. Approval

The first treatment that relies on CRISPR is expected to receive U.S. approval next month. But it may cost millions of dollars per patient.

V.A. Recruits Millionth Veteran for Million Veteran Program Genetic Database

Diverse data from the Million Veteran Program has already contributed to hundreds of medical studies, and the V.A. is continuing to recruit more participants.

New Gene Editing Treatment Cuts Dangerous Cholesterol in Small Study

The trial involved only 10 patients, but it suggests cholesterol can be permanently reduced with a single treatment for patients at risk of heart disease.

F.D.A. Approves New Obesity Drug Tirzepatide That Will Compete With Wegovy

Zepbound, which is already sold by Eli Lilly as the diabetes treatment Mounjaro, was shown to reduce patients’ weight by as much as one-fifth in...

Panel Tells F.D.A. That CRISPR Sickle Cell Cure Is Safe Enough for Patients

The decision by an advisory committee may lead to Food and Drug Administration approval of the first treatment for humans that uses the CRISPR gene-editing...
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